Degree Of Similarity Research Articles

First report of Sclerotium hydrophilum causing leaf spot on Brasenia schreberi in central China.

Brasenia schreberi, commonly known as watershield and referred to as 'Chun Cai' in Chinese, is a worldwide aquatic vegetable. It has long been regarded as health- promoting vegetable due to production of mucilage in young shoots, and thus has gained popularity in China. In September 2022, a leaf spot disease was observed at the National Aquatic Vegetable Germplasm Resource Nursery located in Wuhan, Hubei province, China. The disease occurred on watershield leaves. It started with the formation of leaf spots surrounded by halos.These spots ranged in color from yellow to brown and in diameter from 1 to 10 mm. Subsequently, the smaller spots merged, ultimately causing the entire leaves to turn black. Small brown- to black-colored sclerotia were produced on the underside of the diseased leaves. Disease incidence was 30% on average, and yield loss was approximately 15% on average. To isolate the pathogen, leaf tissues at the disease-healthy border area were excised into 5 × 5 mm pieces, these segments were immersed in 75% ethanol for 30 s, followed by immersion in 0.5% sodium hypochlorite for 30 s, and then rinsed twice in sterile water. After air-drying, the leaf pieces were incubated on potato dextrose agar (PDA) in darkness at 28°C for 3 d. Mycelia from the leaf pieces were transferred to new PDA plates for purification, three sclerotia-forming fungal isolates (Whcc-1, Whcc-3, Whcc-4) were finally obtained. They were incubated on PDA at 28°C for 4 to 14 d for observation of colony morphology. At 4 d after incubation (DAI), they grew rapidly with the average growth rate of 2.2 cm/d and formed colonies with whitish substrate mycelia and well-developed aerial mycelia and small white to light brown-colored sclerotia. At 10 to 14 DAI, the sclerotia gradually turned to black, 0.2 to 0.4 mm in diameter (0.26 mm on average, n = 50). These morphological characteristics matched description of Sclerotium hydrophilum (Bashyal et al. 2021). Molecular identification was done to further clarify the species identity of this fungus. Genomic DNA was extracted from isolates Whcc-1, Whcc-3, and Whcc-4. The internal transcribed spacer region of the ribosomal DNA (ITS-5.8S rDNA) and the small subunit ribosomal RNA gene (ssrRNA) were amplified using universal primers ITS1/ITS4 and NS1/NS6, as described by White et al. (1990). Sequence analysis revealed a high degree of similarity between the ITS-5.8S rDNA sequences from Whcc-1, Whcc-3, and Whcc-4 (GenBank Acc. No. OP782030, PP035994, and PP035995, respectively) and those of S. hydrophilum strain CBS201.27 (GenBank Acc. No. FJ231396), with similarities of 99.25%, 99.4%, and 99.25%, respectively. The ssrRNA sequences from Whcc-1, Whcc-3, and Whcc-4 (GenBank Acc. No. PP238401, PP261342 and PP261345) were found to be identical, displaying 100% similarity to the ssrRNA sequences of S. hydrophilum strain ZH11 (GenBank Acc. No. KC354147). Based on both morphological and molecular evidence, it can be inferred that Whcc-1, Whcc-3, and Whcc-4 belong to the species S. hydrophilum. Pathogenicity tests were conducted by inoculation of the mycelial agar plugs of Whcc-1, Whcc-3 or agar plugs of fresh PDA (control) on floating leaves of two watershield plants, 4 leaves (replicates) for each treatment. After inoculation, the treated leaves were sealed in plastic bags to maintain humidity, and grown under natural conditions (18°C to 28°C, with 8 hours of light daily). At 7 DAI, while control leaves remained healthy, the leaves inoculated with Whcc-1 and Whcc-3 leaves formed yellow- to brown-colored spots similar to those observed in the field surveys. S. hydrophilum was re-isolated from the leaf spots, thus verifing Koch's postulates. S. hydrophilum has a wide host range, infecting at least 19 genera of plants, including common rice and wild rice (Johnson et al. 1976), and water lily (Kernkamp et al. 1977). Moreover, it has been reported to infect rice in China (Punter et al. 1984; Zhong et al. 2018). To our knowledge, this is the first report of S. hydrophilum on watershield leaves in central China.

Proposal of a similarity measure for unified modeling language class diagram images using convolutional neural network

The unified modeling language (UML) represents an essential tool for modeling and visualizing software systems. UML diagrams provide a graphical representation of a system's components. Comparing and processing these diagrams, for instance, can be complicated, especially as software projects grow in size and complexity. In such contexts, deep learning techniques have emerged as a promising solution for solving complex problems. One of these crucial problems is the measurement of similarity between images, making it possible to compare and calculate the differences between two given diagrams. The present work intends to build a method for calculating the degree of similarity between two UML class diagrams. With a goal to provide teachers a helpful tool for assessing students' UML class diagrams.

Optimization and Performance Analysis of CAT Method for DNA Sequence Similarity Searching and Alignment.

Bioinformatics is a rapidly developing field enabling scientific experiments via computer models and simulations. In recent years, there has been an extraordinary growth in biological databases. Therefore, it is extremely important to propose effective methods and algorithms for the fast and accurate processing of biological data. Sequence comparisons are the best way to investigate and understand the biological functions and evolutionary relationships between genes on the basis of the alignment of two or more DNA sequences in order to maximize the identity level and degree of similarity. This paper presents a new version of the pairwise DNA sequences alignment algorithm, based on a new method called CAT, where a dependency with a previous match and the closest neighbor are taken into consideration to increase the uniqueness of the CAT profile and to reduce possible collisions, i.e., two or more sequence with the same CAT profiles. This makes the proposed algorithm suitable for finding the exact match of a concrete DNA sequence in a large set of DNA data faster. In order to enable the usage of the profiles as sequence metadata, CAT profiles are generated once prior to data uploading to the database. The proposed algorithm consists of two main stages: CAT profile calculation depending on the chosen benchmark sequences and sequence comparison by using the calculated CAT profiles. Improvements in the generation of the CAT profiles are detailed and described in this paper. Block schemes, pseudo code tables, and figures were updated according to the proposed new version and experimental results. Experiments were carried out using the new version of the CAT method for DNA sequence alignment and different datasets. New experimental results regarding collisions, speed, and efficiency of the suggested new implementation are presented. Experiments related to the performance comparison with Needleman-Wunsch were re-executed with the new version of the algorithm to confirm that we have the same performance. A performance analysis of the proposed algorithm based on the CAT method against the Knuth-Morris-Pratt algorithm, which has a complexity of O(n) and is widely used for biological data searching, was performed. The impact of prior matching dependencies on uniqueness for generated CAT profiles is investigated. The experimental results from sequence alignment demonstrate that the proposed CAT method-based algorithm exhibits minimal deviation, which can be deemed negligible if such deviation is considered permissible in favor of enhanced performance. It should be noted that the performance of the CAT algorithm in terms of execution time remains stable, unaffected by the length of the analyzed sequences. Hence, the primary benefit of the suggested approach lies in its rapid processing capabilities in large-scale sequence alignment, a task that traditional exact algorithms would require significantly more time to perform.

Organs in orbit: how tissue chip technology benefits from microgravity, a perspective

Tissue chips have become one of the most potent research tools in the biomedical field. In contrast to conventional research methods, such as 2D cell culture and animal models, tissue chips more directly represent human physiological systems. This allows researchers to study therapeutic outcomes to a high degree of similarity to actual human subjects. Additionally, as rocket technology has advanced and become more accessible, researchers are using the unique properties offered by microgravity to meet specific challenges of modeling tissues on Earth; these include large organoids with sophisticated structures and models to better study aging and disease. This perspective explores the manufacturing and research applications of microgravity tissue chip technology, specifically investigating the musculoskeletal, cardiovascular, and nervous systems.

The Effect of Syntactic Similarity on Intra-Sentential Switching Costs: Evidence from Chinese-English Bilinguals.

In order to better understand the role of syntactic similarity in a code-switched sentence, the current study explored the effect of similar and different syntactic structures on Chinese-English bilinguals' intra-sentential switching costs. L2 proficiency and switching directions as factors that potentially intervene in bilingual performance were together explored to see if there was any interaction. We manipulated the degree of syntactic similarity by utilizing clauses in active voice (greater similarity) and passive voice (lesser similarity). The study conducted a self-paced reading paradigm as a more natural language reading processing. Results showed overall longer reading times for active sentences than passive counterparts, which supported a syntactic similarity impediment rather than facilitation. The impediment seemed to be predominant irrespective of L2 proficiency. Furthermore, syntactic similarity modulated the asymmetry of switching costs between forward (L1-L2) and backward (L2-L1) direction: word RTs for the 1st and the 2nd switched word yielded greater costs in L2-L1 condition, while greater costs in L1-L2 condition was observed in 3rd switched word RTs and average RTs. The present study observed syntactic similarity impediment rather than facilitation for Chinese-English bilinguals. Notably, syntactic similarity plays a predominant role compared to L2 proficiency, and modulates the asymmetry between switching directions.

Applicability of electromyography (EMG) as a prospective technique for textural evaluation of different types of biscuits

Bakery industry is an important segment of the food industry, worldwide, and texture is an important determinant in the consumer acceptability of baked products especially biscuits. In this study, six different textured biscuits namely, whole wheat flour biscuit, chocolate biscuit, cumin biscuit, cardamom biscuit, pistachio biscuit and cashew biscuit, procured from local bakery, were analyzed for their proximate composition and color characteristics. The biscuits were having significantly (p ≤ 0.05) different values for proximate composition and color parameters. This study primarily aimed at investigating the application of electromyography (EMG) as a prospective technique for texture evaluation of these different types of biscuits. EMG is an upcoming technique for in vivo food texture evaluation which gives real-time information about the dynamic textural changes occurring during mastication of a food product. The EMG study was conducted on ten human subjects who were served six samples of biscuits in duplicate. To eliminate subject factor variance, two-way ANOVA was applied on the relative values of EMG variables. Two recordings of same subject in an EMG session for a biscuit sample showed significant (p ≤ 0.05) degree of similarity indicating that human mastication behavior is reproducible. Initially, twenty-eight EMG parameters were obtained which were reduced to five representative parameters using cluster analysis. Principal component analysis further classified these five masticatory parameters into two independent principal components (PC1 and PC2) for explaining the data variance. Cumulative proportions for PC1 and PC2 were 37.6% and 70.8%, respectively. The results showed that mastication time obtained from electromyographic analysis can evaluate sensory fracturability, hardness and chewiness. While middle interburst duration can effectively evaluate sensory cohesiveness and instrumental flexural strength. The study concluded that EMG can serve as a comprehensive texture evaluation tool in the bakery industry.

Unveiling the Paradox of Selflessness: Exploring Perceptions of Hypocrisy and Priority Outgroup in Intergroup Moral Dilemmas.

This study examines the impact of prioritizing the out-group in intergroup moral dilemmas. The research aims to achieve three primary objectives: 1) investigating the relationship between out-group prioritization and perceptions of hypocrisy, 2) exploring the influence of perceived hypocrisy and negative emotions on moral judgments, and 3) uncovering the underlying reasons for perceiving outgroup prioritization as hypocritical. Experiments 1, 2 and 3 involved presenting Chinese participants with out-group rescuers and in-group rescuers and asking them to rate the two on three dimensions: level of hypocrisy, level of morality, and negative emotions toward the rescuers. In Experiment 3, the degree of similarity between participants and rescuers was manipulated to control for the level at which participants projected their own intrinsic motivations (ie, self-interest) onto the rescuers. Experiments 1 and 2 jointly showed that participants perceived the out-group rescuer as more hypocritical and immoral compared to the in-group rescuer, and that participants had stronger negative emotions toward the out-group rescuer. Mediation analysis also demonstrated that the perception of hypocrisy and negative emotions largely mediated the relationship between the different rescuers and participants' evaluation of the rescuers' morality. In Experiment 3, participants gave higher hypocrisy ratings to high projection out-group rescuers compared to low projection out-group rescuers. In intergroup dilemmas, choosing to sacrifice the in-group to rescue the outgroup is perceived as more hypocritical, immoral, and objectionable. Perceived hypocrisy arises from an incongruity between individuals' subjective judgments of the rescuers' self-interest motives and the altruistic choice made by the rescuers to rescue the out-group.

Bifurcation analysis of thin-walled structures trimming process with state-dependent time delay

Our previous study [1] revealed that trimming of thin-walled structures has a strongly nonlinear nature, hence this investigation delves into nonlinear dynamic analysis. Specifically, a perturbation method was applied to analyze the linear stability, whilst a direct numerical integration approach was employed to construct bifurcation diagrams, where unsafe cutting caused by multiple stabilities had been found. Basins of attraction were computed to evaluate the cutting safety. Finally, the stability charts for both linearized and fully nonlinear models were constructed showing a good degree of similarity but the linear one has a larger area of stable trimming. The data from our focused experimental studies was then superimposed on both diagrams and it is clear that more refinements in models’ calibration are needed. This work has laid firm foundations for further advanced modelling investigations and experimental studies to gain more insights into nonlinear dynamics of the machining process.

First species record of Strigea falconis Szidat, 1928 (Trematoda, Strigeidae) from gyrfalcon Falco rusticolus in Iceland—pros and cons of a complex life cycle

Strigea falconis is a common parasite of birds of prey and owls widely distributed in the Holarctic. We aimed to characterise S. falconis from Iceland via integrative taxonomic approach and to contribute to the understanding of its circulation in the Holarctic. We recovered adult S. falconis from two gyrfalcons (Falco rusticolus) collected in 2011 and 2012 in Iceland (Reykjanes Peninsula, Westfjords) and characterised them by morphological and molecular genetic (D2 of rDNA, cox1, ND1 of the mDNA) methods. We provide the first species record of S. falconis in Iceland which to the best of our knowledge is its northernmost distributional range. The presence of S. falconis in Iceland is surprising, as there are no suitable intermediate hosts allowing completion of its life cycle. Gyrfalcons are fully sedentary in Iceland; thus, the only plausible explanation is that they acquired their infection by preying upon migratory birds arriving from Europe. Our data indicate that the most likely candidates are Anseriformes and Charadriiformes. Also, we corroborate the wide geographical distribution of S. falconis, as we found a high degree of similarity between our haplotypes and sequences of mesocercariae from frogs in France and of a metacercaria from Turdus naumanni in Japan, and adults from Buteo buteo and Circus aeruginosus from the Czech Republic. The case of Strigea falconis shows the advantages of a complex life cycle and also depicts its pitfalls when a parasite is introduced to a new area with no suitable intermediate hosts. In Iceland, gyrfalcons are apparently dead-end hosts for S. falconis.

Re-evaluating the generic affinity of ‘Silvaroo’ buloloensis (Marsupialia, Macropodidae) from the late Pliocene of Papua New Guinea

Australia and New Guinea have experienced episodic connection and separation by high sea levels since the early Miocene. This has markedly influenced biotic patterns, although exactly how remains puzzling in some instances. One example concerns the palaeozoogeography of forest wallabies (Dorcopsini), all six living species of which are found only in New Guinea, even though most dorcopsin fossils recognized are from Australia. Here we review the taxonomic identity of ‘Silvaroo’ buloloensis from the late Pliocene Otibanda Formation of eastern Papua New Guinea, and show that, according to dental evidence, it is a dorcopsin along with its contemporary, Watutia novaeguineae. Phylogenetic analysis reconstructs ‘S.’ buloloensis as sister to Dorcopsoides fossilis from the late Miocene of central Australia. The degree of dental similarity between them leads us to include it in the same genus. These findings build upon other recent research on extinct New Guinea macropodines, revealing that both forest wallabies and tree-kangaroos are better represented in the fossil record than previously believed, although intriguingly none are ascribable to modern genera. Isaac A. R. Kerr [isaac.kerr@flinders.edu.au], College of Science and Engineering, Flinders University, Bedford Park, South Australia 5042, Australia. Gavin J. Prideaux [gavin.prideaux@flinders.edu.au], College of Science and Engineering, Flinders University, Bedford Park, South Australia 5042, Australia.

Short-Term Response of Ground Beetles (Coleoptera: Carabidae) to Fire in Formerly Managed Coniferous Forest in Central Europe

Forest fires represent a natural element in the dynamics of forest ecosystems. This study investigated the impact of a large-scale forest fire in 2022 (ca. 1300 ha) on epigeic ground beetles (Coleoptera: Carabidae). The research was conducted in coniferous forests at six pairwise study sites: burnt and unburnt dead spruce from bark beetles, burnt and unburnt clear cut, and burnt and unburnt healthy sites. Each site was replicated in four plots, with two pitfall traps deployed within each plot. In total, 48 pitfall traps (6 × 4 × 2) were installed in April 2023. It was tested how individual sites affected the similarity of ground beetle communities, whether they contained similar life guilds, and how significantly large-scale fire affects the abundance of pyrophilous ground beetles. A total of 5952 individuals and 63 species were recorded. We observed a significant decline in abundance at clear-cut and dead spruce burnt sites (73% and 77.5%, respectively) compared to the unburnt sites. Conversely, abundance increased by 88% at the burnt healthy site compared to the unburnt healthy site. Additionally, significant differences in the number of species per trap and species richness diversity (q = 0, q = 1, q = 2) were found only between burnt and unburnt healthy sites. In general, the highest species richness in the comparison of all study sites was at unburnt clear-cut and burnt healthy sites. Communities of ground beetles responded considerably to the fire, differing significantly from unburnt sites, and demonstrating a high degree of similarity. The original healthy spruce stands had highly homogeneous communities. On the contrary, any disturbance (bark beetle calamity, clear-cut) resulted in an increase in the alpha, beta, and gamma diversities of the ground beetle communities. Burnt sites attracted pyrophilous species (Sericoda quadripunctata, Pterostichus quadrifoveolatus) at very low abundances, with the highest activity in the second half of the season. In conclusion, ground beetles demonstrated a strong short-term response to large-scale fire, forming specific communities. However, pyrophilous ground beetles were unable to occupy a large-scale fire area due to the initial low abundance. Understanding post-fire processes can provide important guidance for management in areas designated for biodiversity enhancement.

Structural and functional comparisons of salivary α-glucosidases from the mosquito vectors Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus

Mosquito vectors of medical importance both blood and sugar feed, and their saliva contains bioactive molecules that aid in both processes. Although it has been shown that the salivary glands of several mosquito species exhibit α-glucosidase activities, the specific enzymes responsible for sugar digestion remain understudied. We therefore expressed and purified three recombinant salivary α-glucosidases from the mosquito vectors Aedes aegypti, Anopheles gambiae, and Culex quinquefasciatus and compared their functions and structures. We found that all three enzymes were expressed in the salivary glands of their respective vectors and were secreted into the saliva. The proteins, as well as mosquito salivary gland extracts, exhibited α-glucosidase activity, and the recombinant enzymes displayed preference for sucrose compared to p-nitrophenyl-α-D-glucopyranoside. Finally, we solved the crystal structure of the Ae. aegypti α-glucosidase bound to two calcium ions at a 2.3 Ångstrom resolution. Molecular docking suggested that the Ae. aegypti α-glucosidase preferred di- or polysaccharides compared to monosaccharides, consistent with enzymatic activity assays. Comparing structural models between the three species revealed a high degree of similarity, suggesting similar functional properties. We conclude that the α-glucosidases studied herein are important enzymes for sugar digestion in three mosquito species.

Improving the technology for constructing a software tool to determine the similarity of raster graphic images

The object of research is the process of searching and analyzing images of raster graphics. In the context of this work, the problem of the lack of an effective and fast procedure for determining the similarity of images was solved. The technology for improving the construction of a software tool for determining the similarity of raster graphics images by devising a procedure for determining the similarity of images using a hash code that corresponds to all variants of the image, regardless of size and aspect ratio, is reported. The image features of raster graphics were systematized. A procedure for determining the similarity of images using a hash code is proposed. This procedure makes it possible to process all possible variants of the image, regardless of the size and aspect ratio. The resulting indicator of the proposed procedure is the value of the hash codes. It is proposed to use the mathematical apparatus of fuzzy logic by introducing linguistic variables to estimate the similarity index. A comparison of the numerical values of similarity, obtained on the basis of the use of information systems, and the linguistic values revealed in the survey process was carried out. Threshold values were obtained that make it possible to assess the degree of similarity of the images. Based on the proposed algorithm, a prototype of the information system for determining the similarity of images of raster graphics has been designed. As a result of the calculation of the numerical characteristics of the improvement of the technology of constructing a software tool for determining the similarity of images of raster graphics, the value of the precision indicators was approximately 0.89 and the completeness was 0.8. The advantage of the proposed technology for determining the similarity of images over known analog technologies is illustrated by the amount of RAM of the developed software, which is 210 MB

Слабо-контролируемая групповая классификация

В работе решается задача слабо-контролируемого обучения в постановке групповой бинарной классификации. Предполагается, что каждый объект выборки может включать набор подобъектов, относящихся к разным классам. Предлагаемый метод решения основан на выборе информативного признакового пространства и фильтрации обучающей выборки. Описывается применение разработанного метода для прогнозирования степени поражения участков головного мозга у пациентов с ишемическим инсультом по снимкам компьютерной томографии. Weakly supervised learning implies possible uncertainty or fuzziness of the labelling. Current study addresses this problem using the formulation of group binary classification. It is assumed that each sample object may include a set of sub-objects belonging to one of two classes. Objects are described by a set of features; the predicted feature determines the degree to which an object belongs to the “positive” class. It is required to construct a decision function from the training sample to predict the target feature for new objects. The proposed method is based on the selection of informative feature space and filtering the training sample. Both the selection of informative features and the removal of noise observations are carried out on the basis of analysis of the local environment of objects. The degree of similarity between the object and the class is determined by the k nearest neighbours of the object, taking into account their degree of belonging to the target class. For an experimental study of the developed method, the real problem of analyzing tomography images of the brain to predict the degree of damage to its areas in stroke is solved. The results are compared with a number of known methods. A method for constructing a decision function for predicting the degree of belonging of an object to the target class has been developed. The results of an experimental study and comparison with a number of well-known machine learning algorithms (random forest, support vector machine, kNN) confirmed the efficiency of the method for solving the problem of predicting the degree of damage to brain areas in stroke patients. Unlike other similar algorithms, the proposed method allows establishing a set of the most informative features in order to improve the interpretability of the solution and reduce the effect of overfitting.

The influence of biological relatedness on sexual dimorphism and sex classification based on external morphology of the frontal bone.

The most significant sexual differences in the human skull are located in the upper third of the face (the frontal bone), which is a useful research object, mainly in combination with virtual anthropology methods. However, the influence of biological relatedness on sexual dimorphism and frontal bone variability remains unknown. This study was directed at sexual difference description and sex classification using the form and shape of the external surface of the frontal bones from a genealogically documented Central European osteological sample (nineteenth to twentieth centuries). The study sample consisted of 47 cranial CT images of the adult members of several branches of one family group over 4 generations. Three-dimensional virtual models of the frontal bones were analyzed using geometric morphometrics and multidimensional statistics. Almost the entire external frontal surface was significantly different between males and females, especially in form. Significant differences were also found between this related sample and an unrelated one. Sex estimation of the biologically related individuals was performed using the classification models developed on a sample of unrelated individuals from the recent Czech population (Čechová et al. in Int J Legal Med 133: 1285 1294, 2019), with a result of 74.46% and 63.83% in form and shape, respectively. Failure of this classifier was caused by the existence of typical traits found in the biologically related sample different from the usual manifestation of sexual dimorphism. This can be explained as due to the increased degree of similarity and the reduction of variability in biologically related individuals. The results show the importance of testing previously published methods on genealogical data.

Towards Structural and Aeroelastic Similarity in Scaled Wing Models: Development of an Aeroelastic Optimization Framework

The pursuit of more efficient transport has led engineers to develop a wide variety of aircraft configurations with the aim of reducing fuel consumption and emissions. However, these innovative designs introduce significant aeroelastic couplings that can potentially lead to structural failure. Consequently, aeroelastic analysis and optimization have become an integral part of modern aircraft design. In addition, aeroelastic testing of scaled models is a critical phase in aircraft development, requiring the accurate prediction of aeroelastic behavior during scaled model construction to reduce costs and mitigate the risks associated with full-scale flight testing. Achieving a high degree of similarity between the stiffness, mass distribution and flow field characteristics of scaled models and their full-scale counterparts is of paramount importance. However, achieving similarity is not always straightforward due to the variety of configurations of modern lightweight aircraft, as identical geometry cannot always be directly scaled down. This configuration diversity has a direct impact on the aeroelastic response, necessitating the use of computational aeroelasticity tools and optimization algorithms. This paper presents the development of an aeroelastic scaling framework using multidisciplinary optimization. Specifically, a parametric Finite Element Model (FEM) of the wing is created, incorporating the parameterization of both thickness and geometry, primarily using shell elements. Aerodynamic loads are calculated using the Doublet Lattice Method (DLM) employing twist and camber correction factors, and aeroelastic coupling is established using infinite plate splines. The aeroelastic model is then integrated within an Ant Colony Optimization (ACO) algorithm to achieve static and dynamic similarity between the scaled model and the reference wing. A notable contribution of this work is the incorporation of internal geometry parameterization into the framework, increasing its versatility and effectiveness.

Did Descartes Read Sextus’s Outlines of Pyrrhonism? A Preliminary Study

ABSTRACT This article is an attempt to answer the question whether Descartes had read Sextus Empiricus’s Outlines of Pyrrhonism. At first glance, the question seems trivial. This question, however, is of historico-philosophical significance in that it reveals, even if only partially, what Descartes, who is regarded as the father of early modern philosophy, inherited from his earlier intellectual legacy in formulating his own philosophy. I first compare statements from Sextus’s Outlines with corresponding statements from Descartes’s writings to identify their similarities in terms of content. This comparison focuses on their views regarding four subjects: the syllogistic, moral guidelines, the use of definitions, and true opinions. I then analyse and discuss whether the degree of similarity between these sets of statements is sufficient to conclude that the particular work of Descartes is based on Sextus’s arguments. This preliminary study can only provide indirect evidence that Descartes had read Sextus, for a thorough clarification of whether he read anything other than the works he himself stated that he had read (e.g., Cicero, Suárez), would require further circumstantial evidence, however weak it may be.

Comparative Analysis of the Diagonal Stride Technique during Roller Skiing and On-Snow Skiing in Youth Cross-Country Skiers.

Roller skiing is one primary form of training method as it is an off-snow equivalent to cross-country (XC) skiing during the dry land preseason training, but the results could only be applied to on-snow skiing with appropriate caution. The aim of this present study was to investigate the similarities and differences in roller skiing and on-snow skiing with the diagonal stride (DS) technique. Six youth (age: 14.3 ± 2.9 years) skiers participated in this study. Two high-definition video camcorders and FastMove 3D Motion 2.23.3.3101 were used to obtain the three-dimensional kinematic data. The cycle characteristics and joint angle ROM of the DS technique while skiing on different surfaces were similar. Almost all joint angle-time curves that were obtained from roller skiing showed a moderate-to-high degree of similarity to the angle-time curves obtained from on-snow skiing, except the hip adduction-abduction angle. The differences between roller skiing and on-snow skiing were mainly found in the body and calf anteversion angles, and the joint angles at critical instants. DS roller skiing can simulate DS on-snow skiing to a large extent in youth athletes. The hip movement, knee flexion, and calf anteversion at ski/roller ski touchdown and take-off, pole inclination at pole touchdown, body anteversion angle, and trunk anteversion angle at pole touchdown were the points that required caution when transferring preseason practice roller skiing to on-snow skiing.

New organizational principles and 3D cytoarchitectonic maps of the dorsolateral prefrontal cortex in the human brain.

Areas of the dorsolateral prefrontal cortex (DLPFC) are part of the frontoparietal control, default mode, salience, and ventral attention networks. The DLPFC is involved in executive functions, like working memory, value encoding, attention, decision-making, and behavioral control. This functional heterogeneity is not reflected in existing neuroanatomical maps. For example, previous cytoarchitectonic studies have divided the DLPFC into two or four areas. Macroanatomical parcellations of this region rely on gyri and sulci, which are not congruent with cytoarchitectonic parcellations. Therefore, this study aimed to provide a microstructural analysis of the human DLPFC and 3D maps of cytoarchitectonic areas to help address the observed functional variability in studies of the DLPFC. We analyzed ten human post-mortem brains in serial cell-body stained brain sections and mapped areal boundaries using a statistical image analysis approach. Five new areas (i.e., SFG2, SFG3, SFG4, MFG4, and MFG5) were identified on the superior and middle frontal gyrus, i.e., regions corresponding to parts of Brodmann areas 9 and 46. Gray level index profiles were used to determine interregional cytoarchitectural differences. The five new areas were reconstructed in 3D, and probability maps were generated in commonly used reference spaces, considering the variability of areas in stereotaxic space. Hierarchical cluster analysis revealed a high degree of similarity within the identified DLPFC areas while neighboring areas (frontal pole, Broca's region, area 8, and motoric areas) were separable. Comparisons with functional imaging studies revealed specific functional profiles of the DLPFC areas. Our results indicate that the new areas do not follow a simple organizational gradient assumption in the DLPFC. Instead, they are more similar to those of the ventrolateral prefrontal cortex (Broca's areas 44, 45) and frontopolar areas (Fp1, Fp2) than to the more posterior areas. Within the DLPFC, the cytoarchitectonic similarities between areas do not seem to follow a simple anterior-to-posterior gradient either, but cluster along other principles. The new maps are part of the publicly available Julich Brain Atlas and provide a microstructural reference for existing and future imaging studies. Thus, our study represents a further step toward deciphering the structural-functional organization of the human prefrontal cortex.

Validating EmotiBit, an open-source multi-modal sensor for capturing research-grade physiological signals from anywhere on the body

Peripheral physiological signals provide a powerful window into understanding the body and mind. Peripheral physiology devices that are currently available on the market, however, face a number of challenges. Consumer-grade devices (e.g. FitBit, Apple Watch) are easy to wear, but provide limited access to unprocessed data. Combined with black-box signal processing algorithms, this makes it difficult to interpret the data for scientific research purposes. Research-grade devices (e.g. Empatica, Shimmer, BIOPAC) provide greater access to high-quality data but remain in closed ecosystems and at price points that are out of reach for many. To bridge the gaps in available biometric solutions, our labs have created an open-source physiological sensing platform called EmotiBit (http://www.emotibit.com/), measuring EDA, multi-wavelength PPG, temperature, and 9-axis IMU. This study compares EmotiBit biometric signals to gold-standard devices by Brain Products and finds that the physiological signals exhibit a high degree of similarity, validating their use in research.